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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMPDL3B
All Species:
22.73
Human Site:
Y359
Identified Species:
45.45
UniProt:
Q92485
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92485
NP_001009568.1
455
50814
Y359
T
P
R
W
E
L
E
Y
Q
L
T
E
A
Y
G
Chimpanzee
Pan troglodytes
XP_001151336
455
50854
Y359
M
P
R
W
E
L
E
Y
Q
L
T
E
A
Y
G
Rhesus Macaque
Macaca mulatta
XP_001108274
453
51294
A360
Y
Y
L
N
L
T
E
A
N
L
K
G
E
S
I
Dog
Lupus familis
XP_544464
468
52011
Y371
T
P
L
W
E
L
E
Y
R
L
T
Q
A
Y
G
Cat
Felis silvestris
Mouse
Mus musculus
P58242
456
51581
Y359
T
P
R
W
E
Q
E
Y
R
L
T
E
A
Y
Q
Rat
Rattus norvegicus
Q641Z7
445
49877
L352
L
D
M
L
Q
Y
Y
L
N
L
T
E
A
N
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516772
436
49539
Y337
E
S
N
W
K
L
E
Y
I
L
T
K
A
Y
G
Chicken
Gallus gallus
XP_001232192
454
51318
Y354
V
P
A
W
E
E
E
Y
R
L
T
S
A
F
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_692822
457
52265
Y360
R
A
R
W
E
K
E
Y
R
L
T
E
A
F
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_729555
488
55653
L368
T
W
Q
P
E
Y
N
L
T
H
Y
Y
A
L
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_505620
755
86279
S361
T
P
F
V
F
E
Y
S
F
K
D
A
Y
G
I
Sea Urchin
Strong. purpuratus
XP_786766
452
51341
I359
R
A
T
E
A
Y
N
I
A
D
L
S
P
V
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
40.2
76.2
N.A.
75.6
39.3
N.A.
38
61
N.A.
54.2
N.A.
28.6
N.A.
23.8
39.3
Protein Similarity:
100
99.5
58
83.9
N.A.
86.1
58.4
N.A.
55.8
74
N.A.
71.1
N.A.
47.9
N.A.
37
58
P-Site Identity:
100
93.3
13.3
80
N.A.
80
26.6
N.A.
60
53.3
N.A.
60
N.A.
20
N.A.
13.3
0
P-Site Similarity:
100
93.3
13.3
93.3
N.A.
86.6
33.3
N.A.
73.3
66.6
N.A.
73.3
N.A.
26.6
N.A.
13.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
9
0
9
0
0
9
9
0
0
9
75
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
0
0
0
0
0
0
0
9
9
0
0
0
0
% D
% Glu:
9
0
0
9
59
17
67
0
0
0
0
42
9
0
0
% E
% Phe:
0
0
9
0
9
0
0
0
9
0
0
0
0
17
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
9
0
9
34
% G
% His:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
9
9
0
0
0
0
0
17
% I
% Lys:
0
0
0
0
9
9
0
0
0
9
9
9
0
0
0
% K
% Leu:
9
0
17
9
9
34
0
17
0
75
9
0
0
9
9
% L
% Met:
9
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
9
0
0
17
0
17
0
0
0
0
9
0
% N
% Pro:
0
50
0
9
0
0
0
0
0
0
0
0
9
0
9
% P
% Gln:
0
0
9
0
9
9
0
0
17
0
0
9
0
0
17
% Q
% Arg:
17
0
34
0
0
0
0
0
34
0
0
0
0
0
9
% R
% Ser:
0
9
0
0
0
0
0
9
0
0
0
17
0
9
9
% S
% Thr:
42
0
9
0
0
9
0
0
9
0
67
0
0
0
0
% T
% Val:
9
0
0
9
0
0
0
0
0
0
0
0
0
9
0
% V
% Trp:
0
9
0
59
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
9
0
0
0
25
17
59
0
0
9
9
9
42
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _